Detalhe da pesquisa
1.
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.
Cell
; 183(6): 1617-1633.e22, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259802
2.
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Nature
; 573(7773): 281-286, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31485078
3.
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
Proc Natl Acad Sci U S A
; 117(44): 27354-27364, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067396
4.
HYPERsol: High-Quality Data from Archival FFPE Tissue for Clinical Proteomics.
J Proteome Res
; 19(2): 973-983, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935107
5.
Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss.
Mod Pathol
; 32(10): 1434-1446, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175328
6.
Proteomic approaches for cancer epigenetics research.
Expert Rev Proteomics
; 16(1): 33-47, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30482069
7.
EpiProfile 2.0: A Computational Platform for Processing Epi-Proteomics Mass Spectrometry Data.
J Proteome Res
; 17(7): 2533-2541, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29790754
8.
Preferential Phosphorylation on Old Histones during Early Mitosis in Human Cells.
J Biol Chem
; 291(29): 15342-57, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226594
9.
Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish.
Hepatology
; 64(3): 894-907, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102575
10.
Final phase I substudy results of ivosidenib in patients with mutant IDH1 relapsed/refractory myelodysplastic syndrome.
Blood Adv
; 2024 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38640348
11.
Multicenter Phase I Trial of Ivosidenib as Maintenance Treatment Following Allogeneic Hematopoietic Cell Transplantation for IDH1-Mutated Acute Myeloid Leukemia.
Clin Cancer Res
; 29(11): 2034-2042, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014667
12.
Chromatin-mediated alternative splicing regulates cocaine-reward behavior.
Neuron
; 109(18): 2943-2966.e8, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480866
13.
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation.
Cell Rep
; 33(7): 108390, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33207202
14.
H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.
Cancer Discov
; 10(12): 1968-1987, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967858
15.
Human chimeric antigen receptor macrophages for cancer immunotherapy.
Nat Biotechnol
; 38(8): 947-953, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32361713
16.
Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors.
Cancer Res
; 79(13): 3205-3219, 2019 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30898839
17.
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Nat Commun
; 10(1): 1262, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890717
18.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell
; 35(5): 782-797.e8, 2019 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085178
19.
Characterization of histone acylations links chromatin modifications with metabolism.
Nat Commun
; 8(1): 1141, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070843
20.
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.
Nat Genet
; 49(2): 180-185, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28067913